Japan's National Agriculture and Food Research Organization (NARO), has discovered that by the application of a natural substance named Loliolide to crops such as tomato, the damage caused by pests such as western flower thrips (Frankliniella occidentalis) and two-spotted spider mite (Tetranychus urticae) could be suppressed. Loliolide doesn't have a direct insecticidal effect, but it reduces the pest damage by means of enhancing the pest resistance in tomatoes etc. It is a promising material for pest control agents that utilizes the pest resistance of crops.